منابع مشابه
Aptamer therapy for SCD?
In this issue of Blood, Gutsaeva et al describe an aptamer with high affinity for murine P-selectin and its efficacy in preventing vaso-occlusion in a mouse sickle cell disease (SCD) model.1 Each year, more than 200 000 children are born with SCD,2 yet there is a paucity of treatment options available for sufferers.3 The disease is caused by homozygous expression of a mutation in the beta globi...
متن کاملDli after Allogeneic Bmt for Scd
Volume 40, September 2000 TRANSFUSION 1071 Sickle cell disease (SCD) may be associated with considerable morbidity and mortality, particularly as patients reach adulthood.1 Among the various therapeutic options, allogeneic HPC transplantation is the only treatment with proven curative potential.1,2 However, the underlying disease recurs in about 10 percent of patients.2 Donor lymphocyte infusio...
متن کاملScd Patterns Have Singular Diffraction
Among the many families of nonperiodic tilings known so far, SCD tilings are still a bit mysterious. Here, we determine the diffraction spectra of point sets derived from SCD tilings and show that they have no absolutely continuous part, that they have a uniformly discrete pure point part on the axis Re3, and that they are otherwise supported on a set of concentric cylinder surfaces around this...
متن کاملThe SCD Architecture and its Use in the Design of Story-Driven Interactive Spaces
In this paper we examine story-driven interactive spaces and argue that story development requires centralized control of the actions of the characters that inhabit such environments. This argument leads us to propose the story-character-device (SCD) architecture that, unlike previous approaches, separates the locus of story control in a distinct software module. To exemplify the use of the arc...
متن کاملVibronic structures and dynamics of the predissociating dimethyl sulfide and its isotopomers (CH₃SCH₃, CD₃SCD₃, CH₃SCD₃) at the conical intersection.
Conical intersection seam comprised of crossing surfaces of two lowest excited states of dimethyl sulfide (DMS) has been directly accessed by the one-photon excitation from the ground equilibrium state. Since the S-C bond rupture takes place promptly, the molecular structure on the excited state effectively belongs to C(S) symmetry. Namely, excited states of 1(1)B1 and 1(1)A2 in C(2)V become 1(...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Blood
سال: 2015
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2015-08-666594